Quantity Per Unit - 90
Manufacturer - Designs For Health
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A UNIQUE FORMULA DESIGNED TO HELP SUPPORT HEALTHY BLOOD SUGAR AND
ONLY CHROMIUM SYNERGY GIVES YOU:
* A full 300 mcg of chromium per capsule for its well-documented
benefits on blood sugar and insulin action. Chromium supplementation is
a must for older patients, as chromium levels decline with age.
* Zinc, is a trace mineral needed for healthy blood sugar and insulin
metabolism. Diabetics are often zinc deficient, and zinc is an
essential nutrient needed for the synthesis, storage, secretion, and
conformation integrity of isnulin.
* Manganese, for its benefits on insulin metabolism.
* Taurine, for its insulin-potentiating action.
* Vitamin D, for its insulin and blood sugar supporting benefits.
* Vanadium in a safe, physiologic dose, for its proven benefits on
blood sugar metabolism.
* Cinnamon, for its chalcone polymers which have been found to beneifit
insulin and blood sugar metabolism.
Chromium Nicotinate is Safer Than Chromium Picolinate
Studies have implicated the toxicity of chromium picolinate in renal
impairment, skin blisters and pustules, anemia, hemolysis, tissue
edema, liver dysfunction, neuronal cell injury, impaired cognitive,
perceptual and motor activity, enhanced production of hydroxyl
radicals, chromosomal aberration, depletion of antioxidant enzymes, and
DNA damage. Recently, chromium picolinate has been shown to be
mutagenic and picolinic acid moiety appears to be responsible as
studies show that picolinic acid alone is clastogenic. Niacin-bound
chromium(III) has been demonstrated to be more bioavailable and
efficacious and no toxicity has been reported. In summary, these
studies demonstrate that a cascade of cellular events including
oxidative stress, genomic DNA damage and modulation of apoptotic
regulatory gene p53 are involved in chromium(VI)-induced toxicity and
carcinogenesis. The safety of chromium(III) is largely dependent on the
ligand, and adequate clinical studies are warranted to demonstrate the
safety and efficacy of chromium(III) for human consumption.Chromium
exists mostly in two valence states in nature: hexavalent chromium
[chromium(VI)] and trivalent chromium [chromium(III)]. Chromium(VI) is
commonly used in industrial chrome plating, welding, painting, metal
finishes, steel manufacturing, alloy, cast iron and wood treatment, and
is a proven toxin, mutagen and carcinogen. The mechanistic cytotoxicity
of chromium (VI) is not completely understood, however, a large number
of studies demonstrated that chromium(VI) induces oxidative stress, DNA
damage, apoptotic cell death and altered gene expression. Conversely,
chromium(III) is essential for proper insulin function and is required
for normal protein, fat and carbohydrate metabolism, and is
acknowledged as a dietary supplement. In this paper, comparative
concentration- and time-dependent effects of chromium(VI) and
chromium(III) were demonstrated on increased production of reactive
oxygen species (ROS) and lipid peroxidation, enhanced excretion of
urinary lipid metabolites, DNA fragmentation and apoptotic cell death
in both in vitro and in vivo models. Chromium(VI) demonstrated
significantly higher toxicity as compared with chromium(III). To
evaluate the role of p53 gene, the dose-dependent effects of
chromium(VI) were assessed in female C57BL/6Ntac and p53-deficient
C57BL/6TSG p53 mice on enhanced production of ROS, lipid peroxidation
and DNA fragmentation in hepatic and brain tissues. Chromium(VI)
induced more pronounced oxidative damage in multiple target organs in
p53 deficient mice. Comparative studies of chromium(III) picolinate and
niacin-bound chromium(III), two popular dietary supplements, reveal
chromium(III) picolinate produces significantly more oxidative stress
and DNA damage.
Chromium Synergy offers the best chelated minerals available.
From Albion Advanced Nutrition, the chromium in Chromium Synergy is now
fully chelated to glycine and nicotinic acid for enhanced absorption.
All the nutrients in this formula play different important roles in
insulin function. It is still in a base of cinnamon powder, also known
for its ability to assist bloodsugar control.
What are true chelates?
For minerals to properly form coordinate covalent bonds with the amino
groups of amino acids, they must be mixed in liquid solution. These
bonds cannot form in a dry environment by simply mixing ingredients
together in powdered form. True chelates need to be small enough in
molecular weight to be absorbed by the body (not more than 800
daltons). True chelates are absorbed better than mineral salts and are
better retained in body tissue. Chelates are better tolerated than
non-bound mineral salts. Since they are better tolerated and absorbed
they are less likely to cause loose stools or other gastrointestinal
discomfort. The ligands that the minerals are chelated to are
important, as the chelated compound will remain chelated throughout the
gut and into the bloodstream. Mineral salts from non-true chelates
break apart far sooner, usually in the stomach, leaving the body with
the extra compound to deal with and the mineral in ionic form. Ionic
minerals can interfere with the absorption of other minerals such as
iron and zinc whereas chelated minerals do not. Albion minerals are
with the amino acid glycine due to its low molecular weight. Glycine is
very safe, even in high doses. It helps to slow the degeneration of
muscle tissue by helping to synthesize creatine. Glycine is involved in
energy production, formation of amino acids for the immune system, CNS
function, and prostate health. Studies show some other great benefits
of glycine including accelerating recovery from alcohol-induced liver
Serving Size 1 capsule
Servings Per Container 90
Amount Per Serving % Daily Value
Vitamin D (cholecalciferol) 100 IU 25%
Zinc 10 mg 66% (Chelazome� bis-glycinate chelate)
Manganese 1 mg 50% (Chelazome� bis-glycinate chelate)
Chromium 300 mcg 250% (Chelavite� nicotinate-glycinate chelate)
Taurine 500 mg *
Vanadium 100 mcg *
*Daily Value not established
Other ingredients: Gelatin, cinnamon powder, magnesium
The dietary supplement products offered by ProHealth Solutions are not
intended for us by consumers as a means to cure, treat, prevent,
diagnose, or mitigate any disease or other medical condition.